These States Legalized Weed. More Heart Attacks Followed

These States Legalized Weed. More Heart Attacks Followed

Just about half the country has legalized recreational cannabis, with at least some more states likely to consider it in the near future. But as enjoyable as cannabis can be for many, research out today may highlight a possible drawback of the drug: a higher risk of cardiovascular problems. Researchers in Boston looked at hospitalization … Read more

What causes random chin hairs and what to do about them

What causes random chin hairs and what to do about them

Have you ever caught yourself randomly rubbing your chin, searching for a rogue hair?Those often coarser, darker, unwanted chin hairs are common — affecting nearly half of women — and are determined by your age, genetics, ethnicity and hormonal changes during different stages of life, from puberty through menopause, said Corinne Erickson, an Atlanta-based dermatologist … Read more

Structural basis for protocadherin-1 recognition by New World hantaviruses

Structural basis for protocadherin-1 recognition by New World hantaviruses

Protein purificationSoluble spike proteinsTo produce the soluble spikes of ANDV, we inserted synthetic genes for Gn and Gc of ANDV (strain Chile-9717869, UniProt: Q9E006) codon-optimized for expression in Drosophila cells into a bicistronic plasmid to produce the plasmid p-sSpike. We designed the hetero-octamerization domain starting from HALC4_136, a synthetic homo-tetramerization domain formed by three antiparallel … Read more