The Week 6 college football schedule brings at least one matchup each night, beginning Tuesday and running through Saturday. The highlight is Saturday’s SEC top-10 battle between No. 2 Georgia and No. 6 Alabama in Tuscaloosa, Alabama. Both traditional powers are off to impressive undefeated starts, and the Week 6 college football odds show virtually no gap between them, as Alabama is -1.5 at home after opening as a 2.5-point underdog. Both teams are 4-1 against the spread this season, while Bama has taken three of the last four matchups. Claim Polymarket’s latest promo code, CBSSPORTS, to get a $25 bonus after $10 in trades: Other Week 6 college football highlights include Oregon (-11.5) vs. UCLA as the Ducks will be without QB Dante Moore (concussion), Texas (-8.5) vs. Oklahoma in the Red River Rivalry and LSU (-8.5) at Kentucky. There’s also a showdown of undefeated Big Ten squads when No. 7 Indiana visits Nebraska (+7.5), with the Hoosiers looking for a 6-0 start for the third straight year. Before locking in any Week 6 college football picks on these games or others, be sure to check out the latest college football predictions from SportsLine’s proven model. The model simulates each FBS game 10,000 times. He enters Week 6 with a profitable 40-35 streak on all of the top-rated college football picks on betting sites. Anyone who followed their picks on college football betting sites could have made strong profits. Now, he’s turned his attention to the latest college football odds for Week 6 and set picks for every FBS matchup. Head here to see all the selections. New to sports trading? Visit our Kalshi promo code review and get a $55 bonus after $25 or more in trades with Kalshi promo code CBSSPORTS55: Top College Football Predictions for Week 6 One of the top Week 6 college football picks the model recommends for the best betting apps: Arkansas (+13.5, 50.5) keeps it within double digits at home against No. 15 Tennessee in a matchup at 4:15 p.m. ET on Saturday. The Razorbacks have struggled so far, but showed some signs of progress in Week 4 against Tulsa, winning 34-6 despite being only 7-point favorites in that one. The Vols are tough on defense, but have lacked explosiveness on offense, particularly in the passing game. The Hogs have also won four of the last five meetings, with the only loss coming by just three points. The model projects a one-score win for Tennessee, as the Razorbacks cover over 60% of the time. Another Week 6 prediction: Nebraska (+7.5, 51.5) covers at home against No. 7 Indiana in the noon ET kickoff on Saturday. Indiana is winning, but not dominating the same way the Hoosiers did during their national championship last year. They are just 1-4 against the spread, including a tight win against Northwestern in Week 4. Nebraska, meanwhile, is 4-1 against the spread this season, as the Cornhuskers are coming off back-to-back Big Ten wins and coverages. The model projects a 4-point game as Nebraska covers almost 60% of the time. See what other selections the model likes here. How to Make College Football Picks for Week 6 The model has also decided who wins and covers each Week 6 college football game, and predicts several major upsets. You can only get all the picks for each game at SportsLine. So which college football picks can you confidently make and which underdog teams absolutely win? Check out the latest college football odds below, then visit SportsLine to see which teams are winning and covering the spread, all from a proven computer model that has a 40-35 run, and find out. College Football Odds for Week 6’s Notable Games See the complete Week 6 college football picks, odds and predictions here (odds subject to change) Friday, October 9 Florida State at Louisville (-3.5, 59.5) Iowa at Washington (-3, 41.5) Washington St. at Utah St. (-5.5, 43.5) Wyoming at San Jose St. (-6, 43.5)Iowa St. at BYU (-10.5, 46.5)Saturday, October 10 Indiana at Nebraska (+7.5, 51.5)Texas A&M at Missouri (-3.5, 48.5)South Carolina at Florida (-12.5, 61.5)Ole Miss at Vanderbilt (+9.5, 58.5)Stanford at Notre Dame (-37.5, 53.5)Texas at Oklahoma (+8.5, 39.5)UCLA at Oregon (-11.5, 59.5)Maryland at Ohio State (-34.5, 56.5)Tennessee at Arkansas (+13.5, 50.5)LSU at Kentucky (+8.5, 54.5)Georgia at Alabama (-1.5, 55.5)USC at Penn State (-1.5, 54.5)Minnesota at Purdue (+2.5, 50.5)